Gene: BTLA

Alternate names for this Gene: BTLA1|CD272

Gene Summary: This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.

Gene is located in Chromosome: 3

Location in Chromosome : 3q13.2

Description of this Gene: B and T lymphocyte associated

Type of Gene: protein-coding

rs114092838 in BTLA gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.