Gene: C12orf45

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 12

Location in Chromosome : 12q23.3

Description of this Gene: chromosome 12 open reading frame 45

Type of Gene: protein-coding

Gene: ALDH1L2

Alternate names for this Gene: mtFDH

Gene Summary: This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12q23.3

Description of this Gene: aldehyde dehydrogenase 1 family member L2

Type of Gene: protein-coding

rs7954946 in C12orf45;ALDH1L2 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7304326 in C12orf45;ALDH1L2 gene and Lymphocyte Count measurement PMID 22286170 2012 The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.