Description of this Gene: chromosome 1 open reading frame 141
Type of Gene: protein-coding
rs12044149 in
C1orf141 gene and
Arthritis, Psoriatic
PMID 26626624 2015 Among identified psoriasis risk variants, three were more strongly associated with PsC than PsA (rs12189871 near HLA-C, p = 5.0 × 10(-19); rs4908742 near TNFRSF9, p = 0.00020; rs10888503 near LCE3A, p = 0.0014), and two were more strongly associated with PsA than PsC (rs12044149 near IL23R, p = 0.00018; rs9321623 near TNFAIP3, p = 0.00022).
rs3762318 in
C1orf141 gene and
Blood Protein Measurement
PMID 29875488 2018 Genomic atlas of the human plasma proteome.
rs11209002 in
C1orf141 gene and
Crohn Disease
PMID 17804789 2007 Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.
rs2024825 in
C1orf141 gene and
Leprosy
PMID 25642632 2015 Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.