Gene: CAPN11

Alternate names for this Gene: calpain11

Gene Summary: Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.1

Description of this Gene: calpain 11

Type of Gene: protein-coding

rs7763358 in CAPN11 gene and Vascular Endothelial Growth Factor Measurement PMID 27989323 2017 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.