Gene: CAPN14
Alternate names for this Gene: -
Gene Summary: Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN14 belongs to the calpain large subunit family.[supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: AK296910.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000403897.4/ ENSP00000385247.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##
Gene is located in Chromosome: 2
Location in Chromosome : 2p23.1
Description of this Gene: calpain 14
Type of Gene: protein-coding