Gene: CARD9

Alternate names for this Gene: CANDF2|hCARD9

Gene Summary: The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.

Gene is located in Chromosome: 9

Location in Chromosome : 9q34.3

Description of this Gene: caspase recruitment domain family member 9

Type of Gene: protein-coding

Gene: DNLZ

Alternate names for this Gene: C9orf151|HEP|HEP1|TIMM15|ZIM17|bA413M3.2

Gene Summary:

Gene is located in Chromosome: 9

Location in Chromosome : 9q34.3

Description of this Gene: DNL-type zinc finger

Type of Gene: protein-coding

rs141992399 in CARD9;DNLZ gene and Ankylosing spondylitis PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

rs141992399 in CARD9;DNLZ gene and Cholangitis, Sclerosing PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

rs141992399 in CARD9;DNLZ gene and Crohn Disease PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

rs3829109 in CARD9;DNLZ gene and Fasting blood glucose measurement PMID 22885924 2012 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.

rs3829109 in CARD9;DNLZ gene and Fasting blood sugar result PMID 22885924 2012 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.

rs141992399 in CARD9;DNLZ gene and Psoriasis PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

rs141992399 in CARD9;DNLZ gene and Ulcerative Colitis PMID 26974007 2016 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

rs10870202 in CARD9;DNLZ gene and Vital capacity PMID 28166213 2017 Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.