Gene: CAST

Alternate names for this Gene: BS-17|PLACK

Gene Summary: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene is located in Chromosome: 5

Location in Chromosome : 5q15

Description of this Gene: calpastatin

Type of Gene: protein-coding

Gene: LOC101929710

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs6882366 in CAST;LOC101929710 gene and Body mass index procedure PMID 22344219 2012 Meta-analysis identifies common variants associated with body mass index in east Asians.

rs6882366 in CAST;LOC101929710 gene and Finding of body mass index PMID 22344219 2012 Meta-analysis identifies common variants associated with body mass index in east Asians.