Gene: CBFA2T3

Alternate names for this Gene: ETO2|MTG16|MTGR2|RUNX1T3|ZMYND4

Gene Summary: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Gene is located in Chromosome: 16

Location in Chromosome : 16q24.3

Description of this Gene: CBFA2/RUNX1 partner transcriptional co-repressor 3

Type of Gene: protein-coding

Gene: LOC100129697

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