Gene: CBX7

Alternate names for this Gene: -

Gene Summary: This gene encodes a protein that contains the CHROMO (CHRomatin Organization MOdifier) domain. The encoded protein is a component of the Polycomb repressive complex 1 (PRC1), and is thought to control the lifespan of several normal human cells.

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.1

Description of this Gene: chromobox 7

Type of Gene: protein-coding

rs713909 in CBX7 gene and Lymphocyte Count measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs12158877 in CBX7 gene and Multiple Myeloma PMID 23955597 2013 Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.

PMID 23502783 2013 The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.

PMID 27363682 2016 Genome-wide association study identifies multiple susceptibility loci for multiple myeloma.

rs1005300 in CBX7 gene and Primary amyloidosis PMID 28025584 2017 Genome-wide association study of immunoglobulin light chain amyloidosis in three patient cohorts: comparison with myeloma.

rs139380 in CBX7 gene and Red Blood Cell Count measurement PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs713909 in CBX7 gene and White Blood Cell Count procedure PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.