Gene: CCDC170

Alternate names for this Gene: C6orf97|bA282P11.1

Gene Summary: The function of this gene and its encoded protein is not known. Several genome-wide association studies have implicated the region around this gene to be involved in breast cancer and bone mineral density, but no link to this specific gene has been found.

Gene is located in Chromosome: 6

Location in Chromosome : 6q25.1

Description of this Gene: coiled-coil domain containing 170

Type of Gene: protein-coding

Gene: LOC107986528

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs1038304 in CCDC170;LOC107986528 gene and Bone Density PMID 18445777 2008 Multiple genetic loci for bone mineral density and fractures.

PMID 19079262 2009 New sequence variants associated with bone mineral density.

PMID 19801982 2009 Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.

rs3734805 in CCDC170;LOC107986528 gene and Breast Carcinoma PMID 21263130 2011 We also identified two variants (rs3734805 and rs9383938) mapping to 6q25.1 estrogen receptor 1 (ESR1), which were associated with breast cancer in subjects of northern European ancestry (rs3734805: OR = 1.19, 95% CI = 1.11 to 1.27, P = 1.35 × 10(-7); rs9383938: OR = 1.18, 95% CI = 1.11 to 1.26, P = 1.41 × 10(-7)).

rs3734805 in CCDC170;LOC107986528 gene and Malignant neoplasm of breast PMID 21263130 2011 We also identified two variants (rs3734805 and rs9383938) mapping to 6q25.1 estrogen receptor 1 (ESR1), which were associated with breast cancer in subjects of northern European ancestry (rs3734805: OR = 1.19, 95% CI = 1.11 to 1.27, P = 1.35 × 10(-7); rs9383938: OR = 1.18, 95% CI = 1.11 to 1.26, P = 1.41 × 10(-7)).