Gene: CCKBR

Alternate names for this Gene: CCK-B|CCK2R|GASR

Gene Summary: This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.

Gene is located in Chromosome: 11

Location in Chromosome : 11p15.4

Description of this Gene: cholecystokinin B receptor

Type of Gene: protein-coding

rs2929184 in CCKBR gene and Diastolic blood pressure PMID 30224653 2018 Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.