Gene: CCL27

Alternate names for this Gene: ALP|CTACK|CTAK|ESKINE|ILC|PESKY|SCYA27

Gene Summary: This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.

Gene is located in Chromosome: 9

Location in Chromosome : 9p13.3

Description of this Gene: C-C motif chemokine ligand 27

Type of Gene: protein-coding