Gene: CCR6
Alternate names for this Gene: BN-1|C-C CKR-6|CC-CKR-6|CCR-6|CD196|CKR-L3|CKRL3|CMKBR6|DCR2|DRY6|GPR29|GPRCY4|STRL22
Gene Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
Gene is located in Chromosome: 6
Location in Chromosome : 6q27
Description of this Gene: C-C motif chemokine receptor 6
Type of Gene: protein-coding
Gene: LOC107986672
Alternate names for this Gene:
Gene Summary:
Gene is located in Chromosome:
Location in Chromosome :
Description of this Gene:
Type of Gene:
rs1571878 in
CCR6;LOC107986672 gene and
Rheumatoid Arthritis
PMID 24390342 2014 Genetics of rheumatoid arthritis contributes to biology and drug discovery.
PMID 23143596 2012 High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
PMID 24532676 2015 High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.
PMID 30423114 2019 Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.