Gene: CCT3

Alternate names for this Gene: CCT-gamma|CCTG|PIG48|TCP-1-gamma|TRIC5

Gene Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8.

Gene is located in Chromosome: 1

Location in Chromosome : 1q22

Description of this Gene: chaperonin containing TCP1 subunit 3

Type of Gene: protein-coding

rs148046772 in CCT3 gene and Mean Corpuscular Volume (result) PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

rs148046772 in CCT3 gene and Red Blood Cell Count measurement PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.