Gene: CD163L1
Alternate names for this Gene: CD163B|M160|SCARI2|WC1
Gene Summary: This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene is located in Chromosome: 12
Location in Chromosome : 12p13.31
Description of this Gene: CD163 molecule like 1
Type of Gene: protein-coding
Gene: CD163
Alternate names for this Gene: M130|MM130|SCARI1
Gene Summary: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene is located in Chromosome: 12
Location in Chromosome : 12p13.31
Description of this Gene: CD163 molecule
Type of Gene: protein-coding