Gene: CD63

Alternate names for this Gene: LAMP-3|ME491|MLA1|OMA81H|TSPAN30

Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.2

Description of this Gene: CD63 molecule

Type of Gene: protein-coding