Gene: CD68

Alternate names for this Gene: GP110|LAMP4|SCARD1

Gene Summary: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.1

Description of this Gene: CD68 molecule

Type of Gene: protein-coding

Gene: SENP3-EIF4A1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: EIF4A1

Alternate names for this Gene: DDX2A|EIF-4A|EIF4A|eIF-4A-I|eIF4A-I

Gene Summary:

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.1

Description of this Gene: eukaryotic translation initiation factor 4A1

Type of Gene: protein-coding

rs12942088 in CD68;SENP3-EIF4A1;EIF4A1 gene and RDW - Red blood cell distribution width result PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs12942088 in CD68;SENP3-EIF4A1;EIF4A1 gene and Red cell distribution width determination PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.