Gene: CDC5L

Alternate names for this Gene: CDC5|CDC5-LIKE|CEF1|PCDC5RP|dJ319D22.1

Gene Summary: The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.1

Description of this Gene: cell division cycle 5 like

Type of Gene: protein-coding

rs11571943 in CDC5L gene and Fasting blood glucose measurement PMID 19060907 2009 Variants in MTNR1B influence fasting glucose levels.

rs11572061 in CDC5L gene and Ischemic stroke PMID 26089329 2015 Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans.

rs144085478 in CDC5L gene and Vascular Endothelial Growth Factor Measurement PMID 27989323 2017 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.