Gene: CDC73

Alternate names for this Gene: C1orf28|FIHP|HPTJT|HRPT1|HRPT2|HYX

Gene Summary: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Gene is located in Chromosome: 1

Location in Chromosome : 1q31.2

Description of this Gene: cell division cycle 73

Type of Gene: protein-coding

Gene: LOC101929160

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

rs1558276082 in CDC73;LOC101929160 gene and Parathyroid Gland Adenocarcinoma PMID 20052758 2010 Cell division cycle protein 73 homolog (CDC73) mutations in the hyperparathyroidism-jaw tumor syndrome (HPT-JT) and parathyroid tumors.