Gene: CDCA3

Alternate names for this Gene: GRCC8|TOME-1

Gene Summary:

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.31

Description of this Gene: cell division cycle associated 3

Type of Gene: protein-coding

Gene: USP5

Alternate names for this Gene: ISOT

Gene Summary: Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010].

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.31

Description of this Gene: ubiquitin specific peptidase 5

Type of Gene: protein-coding