Gene: CDCA7L

Alternate names for this Gene: JPO2|R1|RAM2

Gene Summary:

Gene is located in Chromosome: 7

Location in Chromosome : 7p15.3

Description of this Gene: cell division cycle associated 7 like

Type of Gene: protein-coding

Gene: DNAH11

Alternate names for this Gene: CILD7|DNAHBL|DNAHC11|DNHBL|DPL11

Gene Summary: This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility.

Gene is located in Chromosome: 7

Location in Chromosome : 7p15.3

Description of this Gene: dynein axonemal heavy chain 11

Type of Gene: protein-coding

rs7971 in CDCA7L;DNAH11 gene and Breast Carcinoma PMID 29059683 2017 Association analysis identifies 65 new breast cancer risk loci.

rs1128226 in CDCA7L;DNAH11 gene and Multiple Myeloma PMID 23955597 2013 Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.

PMID 22120009 2011 Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk.