Gene: CDCA8

Alternate names for this Gene: BOR|BOREALIN|DasraB|MESRGP

Gene Summary: This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.

Gene is located in Chromosome: 1

Location in Chromosome : 1p34.3

Description of this Gene: cell division cycle associated 8

Type of Gene: protein-coding

rs10908369 in CDCA8 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.