Gene: CDH13

Alternate names for this Gene: CDHH|P105

Gene Summary: This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 16

Location in Chromosome : 16q23.3

Description of this Gene: cadherin 13

Type of Gene: protein-coding

Gene: LOC105371366

Alternate names for this Gene:

Gene Summary:

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rs3096277 in CDH13;LOC105371366 gene and Blood Pressure PMID 17903302 2007 Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.

rs3096277 in CDH13;LOC105371366 gene and Systolic Pressure PMID 17903302 2007 Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.