Gene: CDK10
Alternate names for this Gene: ALSAS|PISSLRE
Gene Summary: The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 16
Location in Chromosome : 16q24.3
Description of this Gene: cyclin dependent kinase 10
Type of Gene: protein-coding
rs258322 in
CDK10 gene and
Hair Color
PMID 18483556 2008 A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.
rs258322 in
CDK10 gene and
Nasopharyngeal carcinoma
PMID 20512145 2010 A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
rs258322 in
CDK10 gene and
melanoma
PMID 21983787 2011 Genome-wide association study identifies three new melanoma susceptibility loci.
PMID 28212542 2017 Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.
PMID 24980573 2014 Identification of a melanoma susceptibility locus and somatic mutation in TET2.
PMID 19578364 2009 Genome-wide association study identifies three loci associated with melanoma risk.
PMID 21926416 2011 Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.
PMID 21706340 2012 A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q.