Gene: CDK14

Alternate names for this Gene: PFTAIRE1|PFTK1

Gene Summary: PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 7

Location in Chromosome : 7q21.13

Description of this Gene: cyclin dependent kinase 14

Type of Gene: protein-coding

rs10953024 in CDK14 gene and Androstenedione measurement PMID 28429243 2017 SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.

rs975004 in CDK14 gene and Common Variable Immunodeficiency PMID 21497890 2011 Genome-wide association identifies diverse causes of common variable immunodeficiency.

rs10953024 in CDK14 gene and ESTRONE MEASUREMENT PMID 28429243 2017 SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.

rs10272859 in CDK14 gene and Hepatitis B PMID 29246937 2018 Genome-Wide Association Study Identifies a New Locus at 7q21.13 Associated with Hepatitis B Virus-Related Hepatocellular Carcinoma.

rs10253488 in CDK14 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs10272859 in CDK14 gene and Liver carcinoma PMID 29246937 2018 This index rs10272859 also showed significant association with the survival of HCC patients.<b>Conclusions:</b> Our findings highlight a novel locus at 7q21.13 conferring both susceptibility and prognosis to HBV-related HCC, and suggest the <i>CDK14</i> gene to be the functional target of the 7q21.13 locus.<i>Clin Cancer Res; 24(4); 906-15.©2017 AACR</i>.

rs67617547 in CDK14 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.