Gene: CDKL3

Alternate names for this Gene: NKIAMRE

Gene Summary: The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.1

Description of this Gene: cyclin dependent kinase like 3

Type of Gene: protein-coding

rs62381364 in CDKL3 gene and Eosinophil count procedure PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.