Gene: CELA2A

Alternate names for this Gene: AOMS4|ELA2A|PE-1

Gene Summary: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.21

Description of this Gene: chymotrypsin like elastase 2A

Type of Gene: protein-coding

Gene: CELA2B

Alternate names for this Gene: ELA2B

Gene Summary: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2B is secreted from the pancreas as a zymogen. In other species, elastase 2B has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.21

Description of this Gene: chymotrypsin like elastase 2B

Type of Gene: protein-coding

Gene: LOC105376767

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

rs1042010 in CELA2A;CELA2B;LOC105376767 gene and Systolic Pressure PMID 28739976 2017 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.