Gene: CFAP298-TCP10L

Alternate names for this Gene: C21orf59-TCP10L|C21orf77|LINC00846

Gene Summary: This locus represents naturally occurring readthrough transcription between the neighboring chromosome 21 open reading frame 59 (C21orf59) and TCP10L (t-complex 10 like) genes on chromosome 21. Readthrough transcripts may encode a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 21

Location in Chromosome : 21q22.11

Description of this Gene: CFAP298-TCP10L readthrough

Type of Gene: protein-coding

Gene: CFAP298

Alternate names for this Gene: C21orf48|C21orf59|CILD26|FBB18|Kur

Gene Summary: This gene encodes a protein that plays a critical role in dynein arm assembly and motile cilia function. Mutations in this gene result in primary ciliary dyskinesia. Naturally occuring readthrough transcription occurs from this locus to the downstream t-complex 10 like (TCP10L) gene.

Gene is located in Chromosome: 21

Location in Chromosome : 21q22.11

Description of this Gene: cilia and flagella associated protein 298

Type of Gene: protein-coding

rs143740376 in CFAP298-TCP10L;CFAP298 gene and Ciliary Motility Disorders PMID 24094744 2013 Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.