Gene: CHRM2

Alternate names for this Gene: HM2

Gene Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7q33

Description of this Gene: cholinergic receptor muscarinic 2

Type of Gene: protein-coding

Gene: LOC349160

Alternate names for this Gene:

Gene Summary:

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rs17168865 in CHRM2;LOC349160 gene and Malignant neoplasm of esophagus PMID 21642993 2011 Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.