Gene: CLCN4
Alternate names for this Gene: CLC4|ClC-4|ClC-4A|MRX15|MRX49|MRXSRC
Gene Summary: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.
Gene is located in Chromosome: X
Location in Chromosome : Xp22.2
Description of this Gene: chloride voltage-gated channel 4
Type of Gene: protein-coding