Gene: CLEC4C

Alternate names for this Gene: BDCA-2|BDCA2|CD303|CLECSF11|CLECSF7|DLEC|HECL|PRO34150

Gene Summary: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.31

Description of this Gene: C-type lectin domain family 4 member C

Type of Gene: protein-coding

rs11055602 in CLEC4C gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs10845821 in CLEC4C gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.