Gene: COL16A1
Alternate names for this Gene: 447AA|FP1572
Gene Summary: This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion.
Gene is located in Chromosome: 1
Location in Chromosome : 1p35.2
Description of this Gene: collagen type XVI alpha 1 chain
Type of Gene: protein-coding
rs2271928 in
COL16A1 gene and
Body mass index
PMID 26426971 2015 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
rs10914462 in
COL16A1 gene and
Intelligence
PMID 29844566 2018 Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
PMID 29326435 2019 A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.