Gene: COL21A1

Alternate names for this Gene: COLA1L|FP633

Gene Summary: This gene encodes the alpha chain of type XXI collagen, a member of the FACIT (fibril-associated collagens with interrupted helices) collagen family. Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 6

Location in Chromosome : 6p12.1|6p12.3-p11.2

Description of this Gene: collagen type XXI alpha 1 chain

Type of Gene: protein-coding

rs9296832 in COL21A1 gene and Blood Pressure PMID 21909110 2011 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.

rs12203179 in COL21A1 gene and Diastolic blood pressure PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

rs12196860 in COL21A1 gene and Other and unspecified reactive psychosis PMID 24132900 2013 Genome-wide association study of atypical psychosis.

rs12196860 in COL21A1 gene and Psychotic Disorders PMID 24132900 2013 Genome-wide association study of atypical psychosis.

rs1925148 in COL21A1 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

rs9475676 in COL21A1 gene and Vital capacity PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.