Gene: COL24A1

Alternate names for this Gene: -

Gene Summary: This gene is a member of the collagen gene family and is thought to regulate type I collagen fibrillogenesis during fetal development.

Gene is located in Chromosome: 1

Location in Chromosome : 1p22.3

Description of this Gene: collagen type XXIV alpha 1 chain

Type of Gene: protein-coding

rs2046158 in COL24A1 gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs12727784 in COL24A1 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs11161721 in COL24A1 gene and Body mass index PMID 28598419 2017 Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth.

rs11161721 in COL24A1 gene and Body mass index procedure PMID 28598419 2017 Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth.

rs11161721 in COL24A1 gene and Finding of body mass index PMID 28598419 2017 Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth.

rs2046159 in COL24A1 gene and Height PMID 21194676 2011 Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

rs7540048 in COL24A1 gene and Low density lipoprotein cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs11161721 in COL24A1 gene and Premature Birth PMID 28598419 2017 We show that maternal COL24A1 variants have a significant genome-wide interaction with maternal pre-pregnancy overweight/obesity on PTB risk, with rs11161721 (P<sub>G × E</sub>=1.8 × 10<sup>-8</sup>; empirical P<sub>G × E</sub>=1.2 × 10<sup>-8</sup>) as the top hit.

rs2046158 in COL24A1 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs7540048 in COL24A1 gene and Serum LDL cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs12076366 in COL24A1 gene and Tonometry PMID 29785010 2018 Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma.

rs313732 in COL24A1 gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

PMID 30575882 2018 Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.