Gene: CPEB1
Alternate names for this Gene: CPE-BP1|CPEB|CPEB-1|h-CPEB|hCPEB-1
Gene Summary: This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants.
Gene is located in Chromosome: 15
Location in Chromosome : 15q25.2
Description of this Gene: cytoplasmic polyadenylation element binding protein 1
Type of Gene: protein-coding
rs150684763 in
CPEB1 gene and
Body Height
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs17507216 in
CPEB1 gene and
Intelligence
PMID 31374203 2019 Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
PMID 29844566 2018 Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
rs17507216 in
CPEB1 gene and
Schizophrenia
PMID 31374203 2019 Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
PMID 28991256 2017 Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
PMID 30285260 2019 Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
PMID 26198764 2015 Genome-wide association study of schizophrenia in Ashkenazi Jews.
rs1145170 in
CPEB1 gene and
Serum albumin measurement
PMID 23281178 2013 A genome-wide assessment of variability in human serum metabolism.