Gene: CPLX1

Alternate names for this Gene: CPX-I|CPX1|EIEE63

Gene Summary: Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.

Gene is located in Chromosome: 4

Location in Chromosome : 4p16.3

Description of this Gene: complexin 1

Type of Gene: protein-coding

rs936551 in CPLX1 gene and Behcet Syndrome PMID 23291587 2013 Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.