Gene: CSDE1

Alternate names for this Gene: D1S155E|UNR

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1p13.2

Description of this Gene: cold shock domain containing E1

Type of Gene: protein-coding

Gene: NRAS

Alternate names for this Gene: ALPS4|CMNS|N-ras|NCMS|NRAS1|NS6

Gene Summary: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Gene is located in Chromosome: 1

Location in Chromosome : 1p13.2

Description of this Gene: NRAS proto-oncogene, GTPase

Type of Gene: protein-coding