Gene: CSRNP1

Alternate names for this Gene: AXUD1|CSRNP-1|FAM130B|TAIP-3|URAX1

Gene Summary: This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 3

Location in Chromosome : 3p22.2

Description of this Gene: cysteine and serine rich nuclear protein 1

Type of Gene: protein-coding

rs1274963 in CSRNP1 gene and Chronic Lymphocytic Leukemia PMID 26956414 2016 Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia.

rs1274963 in CSRNP1 gene and Small Lymphocytic Lymphoma PMID 26956414 2016 Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia.