Gene: CTSZ

Alternate names for this Gene: CTSX

Gene Summary: The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.

Gene is located in Chromosome: 20

Location in Chromosome : 20q13.32

Description of this Gene: cathepsin Z

Type of Gene: protein-coding

Gene: NELFCD

Alternate names for this Gene: HSPC130|NELF-C|NELF-D|TH1|TH1L

Gene Summary: The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini.

Gene is located in Chromosome: 20

Location in Chromosome : 20q13.32

Description of this Gene: negative elongation factor complex member C/D

Type of Gene: protein-coding

rs13720 in CTSZ;NELFCD gene and Platelet Component Distribution Width Measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.