Gene: CXCL1

Alternate names for this Gene: FSP|GRO1|GROa|MGSA|MGSA-a|NAP-3|SCYB1

Gene Summary: This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Gene is located in Chromosome: 4

Location in Chromosome : 4q13.3

Description of this Gene: C-X-C motif chemokine ligand 1

Type of Gene: protein-coding