Gene: CYLD

Alternate names for this Gene: BRSS|CDMT|CYLD1|CYLDI|EAC|MFT|MFT1|SBS|TEM|USPL2

Gene Summary: This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene is located in Chromosome: 16

Location in Chromosome : 16q12.1

Description of this Gene: CYLD lysine 63 deubiquitinase

Type of Gene: protein-coding