Gene: CYP17A1

Alternate names for this Gene: CPT7|CYP17|P450C17|S17AH

Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

Gene is located in Chromosome: 10

Location in Chromosome : 10q24.32

Description of this Gene: cytochrome P450 family 17 subfamily A member 1

Type of Gene: protein-coding

Gene: LOC107984264

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Gene Summary:

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rs10786714 in CYP17A1;LOC107984264 gene and 17 Hydroxyprogesterone measurement PMID 31169883 2019 Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease.

rs10786714 in CYP17A1;LOC107984264 gene and Progesterone measurement PMID 31169883 2019 Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease.