Gene: CYP3A43

Alternate names for this Gene: -

Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 7

Location in Chromosome : 7q22.1

Description of this Gene: cytochrome P450 family 3 subfamily A member 43

Type of Gene: protein-coding

rs80193476 in CYP3A43 gene and Dehydroepiandrosterone sulfate measurement (procedure) PMID 31169883 2019 Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease.