Gene: CYP3A51P

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: CYP3A7-CYP3A51P

Alternate names for this Gene: CYP3A7|CYP3A7-3AP1|CYP3A7-CYP3AP1|CYP3A7.1L|CYPIIIA7

Gene Summary: This locus represents readthrough transcription between the neighboring CYP3A7 (cytochrome P450, family 3, subfamily A, polypeptide 7) and CYP3A51P (cytochrome P450, family 3, subfamily A, polypeptide 51, pseudogene) genes, which are members of the CYP3A gene cluster on chromosome 7. The downstream pseudogene is not known to be independently transcribed. The readthrough transcript includes CYP3A7 exons 1-13 and exons 2 and 13 of the pseudogene. It encodes a CYP3A isoform with a novel C-terminus. This isoform is only expressed in alleles containing a T nucleotide at the -6 position of a splice acceptor in the pseudogene, which enables correct splicing of the upstream CYP3A7 exons to the pseudogene exons. It should be noted that the reference genome sequence represents the CYP3A7_39256 T->A allele, and thus this haplotype is unlikely to produce the readthrough transcript.

Gene is located in Chromosome: 7

Location in Chromosome : 7q22.1

Description of this Gene: CYP3A7-CYP3A51P readthrough

Type of Gene: protein-coding

Gene: CYP3A7

Alternate names for this Gene: CP37|CYPIIIA7|P-450(HFL33)|P-450111A7|P450-HFLA|P450HLp2

Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540.

Gene is located in Chromosome: 7

Location in Chromosome : 7q22.1

Description of this Gene: cytochrome P450 family 3 subfamily A member 7

Type of Gene: protein-coding

Gene: ZSCAN25

Alternate names for this Gene: ZNF498

Gene Summary: This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined.

Gene is located in Chromosome: 7

Location in Chromosome : 7q22.1

Description of this Gene: zinc finger and SCAN domain containing 25

Type of Gene: protein-coding