Gene: CYP4B1

Alternate names for this Gene: CYPIVB1|P-450HP

Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Multiple transcript variants have been found for this gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1p33

Description of this Gene: cytochrome P450 family 4 subfamily B member 1

Type of Gene: protein-coding

rs17102599 in CYP4B1 gene and Serum total cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs17102599 in CYP4B1 gene and Triglycerides measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.