Gene: CYP4F3

Alternate names for this Gene: CPF3|CYP4F|CYPIVF3|LTB4H

Gene Summary: This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Several transcript variants encoding two different isoforms have been found for this gene.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.12

Description of this Gene: cytochrome P450 family 4 subfamily F member 3

Type of Gene: protein-coding

rs10401516 in CYP4F3 gene and Serum albumin measurement PMID 23281178 2013 A genome-wide assessment of variability in human serum metabolism.