Gene: CYP4F8

Alternate names for this Gene: CPF8|CYPIVF8

Gene Summary: This gene, CYP4F8, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and functions as a 19-hydroxylase of prostaglandins in seminal vesicles. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F3, is approximately 18 kb away.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.12

Description of this Gene: cytochrome P450 family 4 subfamily F member 8

Type of Gene: protein-coding

rs3764563 in CYP4F8 gene and C-reactive protein measurement PMID 22228203 2012 A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.