Gene: CYP51A1

Alternate names for this Gene: CP51|CYP51|CYPL1|LDM|P450-14DM|P450L1

Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7q21.2

Description of this Gene: cytochrome P450 family 51 subfamily A member 1

Type of Gene: protein-coding

Gene: CYP51A1-AS1

Alternate names for this Gene: LRRD1-AS1

Gene Summary:

Gene is located in Chromosome: 7

Location in Chromosome : 7q21.2

Description of this Gene: CYP51A1 antisense RNA 1

Type of Gene: ncRNA

rs2229188 in CYP51A1;CYP51A1-AS1 gene and Longevity PMID 25918517 2015 Genetics of aging, health, and survival: dynamic regulation of human longevity related traits.