Gene: DBP

Alternate names for this Gene: DABP|taxREB302

Gene Summary: The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.33

Description of this Gene: D-box binding PAR bZIP transcription factor

Type of Gene: protein-coding

Gene: SPHK2

Alternate names for this Gene: SK 2|SK-2|SPK 2|SPK-2

Gene Summary: This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.33

Description of this Gene: sphingosine kinase 2

Type of Gene: protein-coding