Gene: DCC

Alternate names for this Gene: CRC18|CRCR1|HGPPS2|IGDCC1|MRMV1|NTN1R1

Gene Summary: This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

Gene is located in Chromosome: 18

Location in Chromosome : 18q21.2

Description of this Gene: DCC netrin 1 receptor

Type of Gene: protein-coding

Gene: LINC01917

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 18

Location in Chromosome : 18q21.2

Description of this Gene: long intergenic non-protein coding RNA 1917

Type of Gene: ncRNA